From the UK:
There are regular flights to Logan International Airport from the main UK airports, and the flight from London takes between 7 and 8 hours.
It is in East Boston a few kilometers from downtown. All major U.S. carriers serve Boston Logan with extensive direct connections nationwide. Many European carriers also fly to Boston from their hubs including British Airways and Virgin Atlantic (London), Air France (Paris), Alitalia (Rome), Lufthansa (Frankfurt, Munich), Aer Lingus (Dublin, Shannon), Swiss (Zurich), Icelandair (Reykjavik), Iberia (Madrid) and Delta/KLM (Amsterdam). Getting to Boston from Asia will require at least a one stop connection.